Biologically Active Small Molecules, Cayman Chemical, 301836-41-9

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  • Cayman Chemical

    A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM), ALK4 (IC50 = 140 nM) and, less effectively, ALK7; suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.