Biologically Active Small Molecules, Cayman Chemical, 23593-75-1, 1 g
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Clotrimazole
Cayman ChemicalAn imidazole antifungal; tightly binds sterol 14-α demethylase isoform B from A. fumigatus (KD = 103 nM) and disturbs the fungal cell membrane; inhibits the calcium-dependent potassium channels Kv1.3 and IK-1 (IC50 = 6.0 and 0.07 µM, respectively) in mammalian cells.
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