Biologically Active Small Molecules, 944261-79-4, 1.0 mg
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A-803467
Cayman ChemicalA sodium channel blocker with high-affinity and selectivity for inhibiting human Nav1.8 sodium channels (IC50 = 8 nM when stimulated at half-maximal inactivation and IC50 = 79 nM at a resting state); dose dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models.
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