765317-72-4
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PTP1B Inhibitor
Thermo Scientific ChemicalsSynonym(s): 3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(2-thiazolylsulfamoyl)phenyl]benzofuran-6-sulfonamide Formula: C26H19Br2N3O7S3 Formula weight: 741.45 CAS Number: 765317-72-4 Harmonized Tariff Code: 3504.00
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PTP1B Inhibitor
Cayman ChemicalA cell-permeable allosteric inhibitor of PTP1B (IC50s = 4 and 8 µM for 403 and 298 residue PTP1B forms, respectively); binds reversibly and non-competitively; selectively increases the phosphorylation of the insulin receptor, insulin receptor substrate 1, and Akt, mimicking the…
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