765317-72-4, 1 mg
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PTP1B Inhibitor
Cayman ChemicalA cell-permeable allosteric inhibitor of PTP1B (IC50s = 4 and 8 µM for 403 and 298 residue PTP1B forms, respectively); binds reversibly and non-competitively; selectively increases the phosphorylation of the insulin receptor, insulin receptor substrate 1, and Akt, mimicking the…
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