A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of…

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by Phytolab GmbH & Co. KG Synonyms: Paclitaxel Molecular Formula: …

Formula: C47H51NO14 Formula weight: 853.91 Purity: 99.5+% CAS Number: 33069-62-4 Harmonized Tariff Code:  2932.99 Hazard Statements: H301-H311-H334-H341-H361-H318-H332-H315-H317-H335 Toxic if swallowed. Toxic in contact with skin. May cause allergy or asthma symptoms or breathing…

Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle…

Empirical Formula: C₄₇H₅₁NO₁₄ Linear Formula: C₄₇H₅₁NO₁₄ Formula Weight: 853.91 MDL Number: MFCD00869953 Melting Point: 213 °C (dec.)(lit.) Storage: 2-8°C Beilstein Registry Number: 1420457

Paclitaxel has been used as a component of the dechorionation buffer for Gryllus bimaculatus eggs. Paclitaxel has also been used for studying its effect on the movement of all-trans retinoic acid (ATRA) differentiated NB4 cells. Antitumor and antileukemic agent which lowers the critical…