Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants. Based on stationary phases composed of 10µm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.
Multiple Formats for Greater Flexibility
- ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group
- Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semi-prep work
Superior Performance for Protein Analysis
- Ideal for characterization and quality control assessment of MAbs and other proteins
- Well-suited for characterization of related protein variants including deamidation and MAb lysine truncation variants
- Unequaled high-resolution separations
- Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing