Trehalose is a natural alpha-linked non–reducing disaccharide formed by an α,α-1,1-glucoside bond between two α-glucose units which yields 2 moles of D-glucose upon acid hydrolysis. Has 90% of the calorific content of sucrose. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
Use as a cryoprotectant in a variety of cell freezing media.
Trehalose is a non-reducing sugar formed from two glucose units joined by a 1-1 alpha bond. It is thought to provide plants and animals with the ability to withstand periods of dehydration.
Purity: ≥99%
Key Applications: Protein-stabilizing agent in research
Product Type: Biochemicals
Biochemical Category: Carbohydrates
Presentation: White Powder
Loss on Drying: ≤8.5 - 10.5%
Solubility: Soluble in water (50 mg/mL - clear, colorless solution) or hot alcohol.
Storage & Handling: Room Temperature