Synonyms: 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis1-dodecanone
Molecular Formula: C45H62O8
Molecular Weight: 730.97
Linear Structural Formula: C45H62O8
MDL Number: MFCD00918068
Purity: >=95% (HPLC)
Storage: -20C
Biochem Physiol Actions: YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. The IC50 against rabbit platelet derived sPLA2 is 85 nM. YM-26734 is active against, but less potent for group I (pancreatic) sPLA2 (porcine pancreatic enzyme IC50 = 7 muM), and does not inhibit intracellular PLA2 isoforms.