Synonyms: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin; Coumafene
CAS Number: 81-81-2
Formula: C19H16O4
Formula Weight: 308.33
Linear Formula: C19H16O4
MDL No.: MFCD00006854
Melting Point: 162-164 C (lit.)
Beilstein Registry Number: 8868198
EC Number: 201-377-6
UNSPSC Code: 41116107
Application: Refer to the product's Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Application: Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food.
Biochem/physiol Actions: Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z.
RTECS: GN4550000
RIDADR: UN2811 - class 6.1 - PG 1 - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany: 3
R Codes: 61-21-28-48/25-52/53
S Codes: 53-28-36/37-45-61
IOD Codes: T+
Symbol: GHS06, GHS08, GHS09
Signal Word: Danger
Hazard Statements: H300 + H310 + H330-H360D-H372-H411
Precautionary statements: P201-P260-P262-P273-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310-P308 + P313-P391-P403 + P233