Native beta2-microglobulin from human urine. Single chain polypeptide that is the constant component of Class I MHC, which is located on most nucleated cells. It is also a normal constituent of serum and urine. Increased levels of this protein in the serum are used as a marker for impairments of renal function and a variety of lymphoproliferative diseases.
Synonyms: beta₂M
Purity: >=98% (SDS-PAGE)
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Other Notes: Zabay, J.M., et al. 1995. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 8, 266.Mady, B.J., et al. 1991. J. Immunol.147, 3139.Lampson, L.A. 1990. J. Immunol. 144, 512.Calzia, R., et al. 1989. Adv. Exp. Med. Biol.257, 225.Ninomiya, Y., and Arakawa, M. 1989. Diabetes Res.10, 129.