Synonyms: 16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
Formula: C25H34O6
Formula Weight: 430.53
CAS No.: 51333-22-3
General description: This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO Guide 34.
Biochem/physiol Actions: Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.
Other Notes: Values of analytes vary lot to lot.
Grade: certified reference material
Packaging: pkg of 500 mg
Pharmacopeia Traceability: traceable to BP 793