=99% (HPLC and TLC), BioXtra, for molecular biology
Synonym: ?,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid ?-lactone, Ascotoxin, BFA, Cyanein, Decumbin
CAS Number 20350-15-6
Empirical Formula (Hill Notation) C16H24O4
Molecular Weight 280.36
Beilstein Registry Number25191
MDL number MFCD12913297
PubChem Substance ID 24891917
Quality Level : PREMIUM
biological source: from Penicillium brefeldianum
grade for molecular biology
product line BioXtra
assay: =99% (HPLC and TLC)
storage temp. 2-8°C
Biochem/physiol Actions
? Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.