Molecular Formula: C14H26N2O6
Molecular Weight: 318.37
Linear Structural Formula: C14H26N2O6
Purity: >=95%
Density: 1.1544 g/mL
Refractive Index: n/D 1.4567
Application: This hydroxylamine derivative readily reacts with potassium acyltrifluoroborates (KATs) to chemoselectively form amide bonds under aqueous conditions. Once incorporated into peptides, the Boc-hydroxylamine is stable to unprotected primary amines and conditions needed for ligation, deprotection, or Fmoc cleavage. The presence of the hydroxylamine on your peptide or protein enables the chemoselective conjugation of any of the several KAT analogues introduced collaboratively with the Jeff Bode Research Group.
Other Notes: Rapid Ligations with Equimolar Reactants in Water with the Potassium Acyltrifluoroborate (KAT) Amide Formation