Synonyms: (3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-Indole-6-carboxamide
Molecular Formula: C25H24N4O2
Molecular Weight: 412.48
Linear Structural Formula: C25H24N4O2
MDL Number: MFCD18157583
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: BIX02188 is a potent and selective inhibitor of MEK5 with IC50 of 4.3 nM. BIX02188 also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.