The ET peptide family consists of three isoforms, ET-1 (corresponding to the initially isolated and most predominant isoform), ET-2, and ET-3. ET-1 is a 21 amino acid peptide and is one of the most potent vasoconstrictors currently known. ET-2 displays similar pharmacology to ET-1, whereas ET-3 is a weak vasoconstrictor but more potent inhibitor of platelet aggregation. Cayman’s ET Assay offers sensitive and specific analysis of ET in serum, plasma, urine, or cell culture media.