Synonyms: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide; Actidione; Naramycin A
CAS Number: 66-81-9
Formula: C15H23NO4
Formula Weight: 281.35
Linear Formula: C15H23NO4
MDL No.: MFCD00082346
Purity: >=94% (TLC)
Storage: 2-8C
Beilstein Registry Number: 88868
EC Number: 200-636-0
UNSPSC Code: 12352200
Application: . In yeast strains, cycloheximide has been used as a protein synthesis inhibitor in the cycloheximide chase experiment. . It has been used to inhibit translation in mammalian cells.. It has been used to suppress fungal growth.
Biochem/physiol Actions: Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.
Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
RTECS: MA4375000
RIDADR: UN2811 - class 6.1 - PG 2 - EHS - Toxic solids, organic, n.o.s., HI: all
WGK Germany: 3
R Codes: 61-28-51/53-68
S Codes: 53-45-61
IOD Codes: T+,N
Symbol: GHS06, GHS08, GHS09
Signal Word: Danger
Hazard Statements: H300-H341-H360D-H411
Precautionary statements: Missing Phrase - N15.00950417-P201-P280-P308 + P313