Antigen: CHO cells transfected with human TLR2 cDNA
Host: mouse, clone TL2.1
Cross Reactivity: (+) human and canine TLR2
Application(s): FC (intracellular and cell surface), ICC, IHC, IP, and WB
TLR2 interacts with TLR1 and coexpression of TLR1 and TLR2 enhances the NF-kB activation in response to a synthetic lipopeptide. Together, they recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.