Antigen: fusion protein amino acids 2-101 of human KCNQ1
Host: mouse, clone S37A-10
Isotype: IgG1
Cross Reactivity: (+) human, mouse, and rat KCNQ1
Application(s): ICC, IHC, IP, and WB
Kv7.1 (KvLQT1) is a potassium channel protein coded by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying potassium) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart’s contraction.