Antigen: synthetic peptide corresponding to the residues of human FKBP52
Host: mouse, clone Hi52C
Isotype: IgG1
Cross Reactivity: (+) canine, hamster, human, mouse, and rat FKBP52
Applications: IHC (paraffin embeded sections), IP, and WB
FKBP52 is part of the mature glucocorticoid receptor heterocomplex. The N-terminal domain binds FK506 and has peptidyl-prolyl isomerase activity that converts prolyl peptide bonds within target proteins from cis- to trans- proline. The C-terminal domains contain the TRP repeats involved in protein-protein interactions with Hsp40.