EPO, human: Human Erythropoietin Erythropoietin (EPO), a glycoprotein produced primarily by the kidney, is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The production of EPO by kidney cells is increased in…

TNF alpha, Tumor Necrosis Factor-alpha, human: Human Tumor Necrosis Factor-alpha Tumor necrosis factor alpha (TNF-α), also called cachectic, is produced by neutrophils, activated lymphocytes, macrophages, NK cells, LAK cells, astrocytes endothelial cells, smooth muscle cells and some…

EGF, Epidermal Growth Factor, human: Human Epidermal Growth Factor  EGF was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting…

IL-11, Interleukin-11, human: Interleukin 11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive murine plasmacytoma cell line T1165. IL-11 was also…

Description: EcoCRM™ is CRM₁₉₇ produced as a soluble intracellular protein in E. coli. CRM₁₉₇ is genetically detoxified diphtheria toxin. Specifically, it has a single amino acid substitution (glycine52 to glutamic acid), which causes the ADPribosyltransferase activity…

Description: Recombinant, tag-free, purified marburgvirus (MARV) matrix protein (VP40) is expressed in E. coli and the recombinant protein purified using FPLC. Size: 100 µg of protein is supplied in HEPES buffer pH 7.5 containing sodium chloride, 5% glycerol and 0.1% Triton-X, at a…

IL-4, Interleukin-4, human: Human Interleukin-4 Interleukin-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of…

The Bio Basic MIP-1 Beta, CCL4, Human is suitable for use in laboratory use only. It can be stored at a temperature of -15 to 20 degree C.

IL-1 beta, Interleukin-1 beta, porcine: Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and…

IL-1 beta, Interleukin-1 beta, monkey (rhesus macaque): IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not…

IL-1 beta, Interleukin-1 beta, human: Human Interleukin-1 beta  IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has…

MIP-1 beta, CCL4, murine (mouse): Chemokine (C-C motif) ligand 4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a monokine with…

GM-CSF, Granulocyte Macrophage Colony Stimulating Factor, murine (mouse): Mouse GM-CSF GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocytemacrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil…

GMF beta, rat: Glia Maturation Factor beta (GMF-β), a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the…

BMP-4, Bone Morphogenetic Protein-4, human: Human BMP-4 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor β (TGF-β) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.…

sCD40 Ligand, TRAP, rHusCD40L, human: CD40 ligand, CD40L (also known as CD154, TRAP or gp39), is a 261 amino acid type II transmembrane glycoprotein belonging to the TNF family, CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, like NK cells,…

Description: Recombinant, tag-free, purified Ebola virus (EBOV) matrix protein (VP40) is expressed in E. coli and the recombinant protein purified using FPLC. Size: 100 µg of protein is supplied in HEPES buffer pH 7.5 containing sodium chloride, 5% glycerol and 0.1% Triton-X, at a…

BD-4, rat: Defensins (alpha and beta) are cationic peptides with antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses. They are 2-6 kDa proteins and take important roles in innate immune system. On the basis of their size and pattern of…

IFN beta 1b, Interferon beta 1b, human: Human Interferon-β  Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and…

Description: Recombinant, tag-free, purified Sudan virus (SUDV) matrix protein (VP40) is expressed in E. coli and the recombinant protein purified using FPLC. Size: 100 µg of protein is supplied in HEPES buffer pH 7.5 containing sodium chloride, 5% glycerol and 0.1% Triton-X, at a…

Description: Virus-like Particles (VLP’s) expressing recombinant Sudan virus (SUDV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). These VLP’s are produced in Sf9 insect cells through infection with a recombinant baculovirus. Size: 1 mg of protein supplied in…

IL-13, Interleukin-13, murine (mouse): IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of…

FGF-10, Fibroblast Growth Factor-10, human: KGF-2(also known as FGF-10) was originally identified from rat embryos by homology-based polymerase chain reaction. Human and mouse KGF-2 were subsequently cloned. The human KGF-2 cDNA encodes a 208 amino acid residue protein with a hydrophobic…

IL-12, Interleukin-12, human: Interleukin 12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has…

Description: Purified Staphylococcus aureus phenol soluble modulin (PSM-α3) peptide Size: 100 µg is supplied in phosphate buffered saline at a concentration of 1.15 mg/mL. Relevance: S. aureus secretes four short (~20 amino acids) α-type phenol soluble modulins of which…

FGF-basic, Fibroblast Growth Factor-basic, human: Human Fibroblast Growth Factor-basic FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35 - 60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are…

IL-3 beta, Interleukin-3-beta, rat: Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced…

Description: Recombinant, Influenza Hemagglutinin Full-Length Glycoprotein (rHA GP) from virus strain A/Hong Kong/33982/2009 (H9N2). Recombinant HA is supplied as an affinity purified protein. rHA is produced in Sf9 insect cells using baculovirus for expression and is purified by FPLC. Size: …

GMF beta, Glia Maturation Factor beta, murine (mouse): The glia maturation factor beta belongs to the actin-binding proteins ADF family, GMF subfamily. It contains an ADF-H domain, but the research of crystallography and NMR reveals that there are structures different between human and mouse…

MIF, Migration Inhibitor Factor, human: Migration Inhibitory Factor (MIF) is a secreted protein without a cleavable signal sequence and is secreted via a specialized, non-classical pathway. It is secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.…

IFN gamma, Interferon gamma, murine (mouse): Interferon-gamma (IFN-γ, also known as Type II interferon or immune interferon) is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-β or the various IFN-α…

FGF-basic, Fibroblast Growth Factor-basic, rat: FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and…