Description: Purified Staphylococcus aureus phenol soluble modulin (PSM-α3) peptide
Size: 100 µg is supplied in phosphate buffered saline at a concentration of 1.15 mg/mL.
Relevance: S. aureus secretes four short (~20 amino acids) α-type phenol soluble modulins of which the PSM- α3 plays the most prominent role in S. aureus virulence. PSM toxin is a major virulence factor of S. aureus and primarily causes cytolysis in red and white blood cells
Recommended Dilutions:
ELISA: Assay-dependent dilution.
WB: Not recommended for this peptide.
Cytotoxicity assay: The peptide is active in functional lysis assays with horse red blood cells and human neutrophils (Data not shown). Lytic activity towards human or rabbit RBC for this product has not been tested. The peptide can be also used in serology assay as coating antigen to detect antibodies to PSM.
Storage: -20°C
Intended for research use only, not for human, therapeutic, or diagnostic applications.