UN3462, 100 µg
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Bafilomycin B1
Cayman ChemicalA selective, reversible inhibitor of V-ATPases in mammalian, plant, or fungal cells with an IC50 value in the 4-400 nM range; at 100 nM, the related bafilomycin A1 blocks V-ATPase-mediated acidification of lysosomes during autophagy, preventing protein degradation.
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Microcystin-LA
Cayman ChemicalDiffers from the major microcystin variant LR with the substitution of alanine in place of the arginine; inhibits both PP1C and PP2A with an IC50 value of 0.3 nM.
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Aflatoxin M1
Cayman ChemicalA natural oxidative metabolic of the mycotoxin aflatoxin B1; produced from aflatoxin B1 in mammals and then secreted in milk.
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Gilvocarcin V
Cayman ChemicalAn antitumor antibiotic that inhibits DNA synthesis by promoting the selective cross-linking of both histone H3 and the heat shock protein, GRP78 to DNA when photoactivated by near-UV or visible light.
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Okadaic acid potassium salt, 98%
Thermo Scientific ChemicalsFormula: C44H67KO13 Formula weight: 843.11 Purity: 98% CAS Number: 155751-72-7 UN Number: UN3462 Hazard Class: 6.1 Packing Group: I Harmonized Tariff Code: 2932.19 Hazard Statements: H300-H310-H330-H315 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.…
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Concanamycin A
Cayman ChemicalBlocks lysosomal acidification through selective inhibition of the V-type ATPase (EC50 = 2.1-2.3 μM); blocks cell surface expression of viral glycoproteins without affecting their synthesis and, at 0.8 μM, prevents entry of influenza virus into cells.