A non-selective NSAID exhibiting IC50 values of 0.5 and 2.33 µM for human recombinant COX-1 and COX-2, respectively.

An NSAID thought to exert its actions by a prostanoid-independent mechanism; inhibits fMLP- and A23187-induced Ca2+ influx in human neutrophils with an IC₅₀ value of approximately 20 µM.

Niflumic acid is a selective inhibitor of COX-2. The IC₅₀ values are 16 and 0.1 µM for human recombinant COX-1 and -2, respectively. The Ki values are 2 and 0.02 µM for ovine COX-1 and -2, respectively.

A non-selective COX inhibitor; inhibits human recombinant COX-1 and -2 with IC₅₀ values of 0.04 and 0.51 µM, respectively.

A non-selective inhibitor of both COX-1 and COX-2 with extensive epidemiology documenting its effective reduction of human colorectal cancer.