Synonym(s): FK-506, Fugimycin Formula: C44H69NO12 Formula weight: 804.02 Purity: 99+% CAS Number: 104987-11-3 UN Number: UN2811 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2934.99 Hazard Statements: H301 Toxic if swallowed. Precautionary Statements: …

A potent, clinically-useful immunosuppressant; binds to FK-506 binding protein 12 (Ki = 0.2 nM) to inhibit calcineurin; regulates NO neurotoxicity, neurotransmitter release, and regulation of Ca2+ release via the ryanodine and IP3 receptors.