Bottle, Poly, SouthernBiotech, 0.5 mg
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SouthernBiotech Rat Anti-Mouse CD19-FITC
SouthernBiotechCD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…
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SouthernBiotech Rat Anti-Mouse CD117-FITC
SouthernBiotechThe CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…
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SouthernBiotech Rat Anti-Mouse Ly-6G/Ly-6C-UNLB
SouthernBiotechLy-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the…
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SouthernBiotech Rat Anti-Mouse CD18-LE/AF
SouthernBiotechCD18 represents the common ß2 integrin subunit that associates non-covalently with the a/ß chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic…
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SouthernBiotech Hamster Anti-Mouse CD28-BIOT
SouthernBiotechCD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86…
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SouthernBiotech Rat Anti-Mouse CD45RB-FITC
SouthernBiotechCD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.
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SouthernBiotech Rat Anti-Mouse CD22-BIOT
SouthernBiotechCD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage),…
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SouthernBiotech Mouse Anti-Mouse CD72.1-BIOT
SouthernBiotechMurine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and…
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SouthernBiotech Rat Anti-Mouse CD71-BIOT
SouthernBiotechCD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and…
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SouthernBiotech Hamster Anti-Mouse CD79b-BIOT
SouthernBiotechMurine CD79 is a disulfide-linked heterodimer composed of an a chain (CD79a) and a ß chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B…
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SouthernBiotech Hamster Anti-Mouse CD103-UNLB
SouthernBiotechThe monoclonal antibody 2F1 reacts with mouse killer cell lectin-like receptor G1 (KLRG1; formerly known as mouse MAFA), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their…
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SouthernBiotech Rat Anti-Mouse CD40-FITC
SouthernBiotechCD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first…
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SouthernBiotech Rat Anti-Mouse CD24-UNLB
SouthernBiotechCD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory…
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SouthernBiotech Hamster Anti-Mouse CD28-UNLB
SouthernBiotechCD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86…
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SouthernBiotech Hamster Anti-Mouse TCRgd-BIOT
SouthernBiotechThe TCR?d heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of ?d TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial…
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SouthernBiotech Rat anti-Mouse CD40-BIOT
SouthernBiotechCD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first…
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SouthernBiotech Hamster Anti-Mouse CD79b-LE/AF
SouthernBiotechMurine CD79 is a disulfide-linked heterodimer composed of an a chain (CD79a) and a ß chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B…
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SouthernBiotech Rat Anti-Mouse CD38-FITC
SouthernBiotechMurine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR) and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral…
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SouthernBiotech Rat Anti-Mouse CD45RB-BIOT
SouthernBiotechCD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.
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SouthernBiotech Rat Anti-Mouse CD38-UNLB
SouthernBiotechMurine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR) and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral…
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SouthernBiotech Hamster Anti-Mouse CD152-FITC
SouthernBiotechThe lymphocyte surface antigen CD152, also known as CTLA-4, is related to the costimulatory molecule CD28 and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152…
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SouthernBiotech Mouse Anti-Mouse I-Ek-FITC
SouthernBiotechThe monoclonal antibody 14-4-4S reacts with the I-Ek class II alloantigen on cells from mice of the H-2d, H-2p, and H-2r haplotypes. Cells from mice of the H-2b, H-2f, H-2q, and H-2s haplotypes do not express I-E antigen. The antibody has been reported to cross-react with the rat MHC class II…
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SouthernBiotech Rat Anti-Mouse Ly-6G/Ly-6C-BIOT
SouthernBiotechLy-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the…
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SouthernBiotech Rat Anti-Mouse CD104-LE/AF
SouthernBiotechCD45RC represents an exon C-dependent isoform of CD45 glycoprotein. It is expressed at high density on all B lymphocytes, at intermediate density on most CD8+ splenic T cells, and on two subpopulations of CD4+ splenic T cells with high and low density of expression. CD45RC is also present on a…
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SouthernBiotech Rat Anti-Mouse CD40-UNLB
SouthernBiotechCD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first…
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SouthernBiotech Hamster Anti-Mouse KLRG1-UNLB
SouthernBiotechThe monoclonal antibody 2F1 reacts with mouse killer cell lectin-like receptor G1 (KLRG1; formerly known as mouse MAFA), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their…
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SouthernBiotech Mouse Anti-Mouse CD19-UNLB
SouthernBiotechCD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…
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SouthernBiotech Hamster Anti-Mouse TCRgd-LE/AF
SouthernBiotechThe TCR?d heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of ?d TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial…
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SouthernBiotech Mouse Anti-Mouse CD72.1-FITC
SouthernBiotechMurine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and…
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SouthernBiotech Rat Anti-Mouse CD90.2-BIOT
SouthernBiotechCD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The…
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SouthernBiotech Hamster Anti-Mouse CD69-BIOT
SouthernBiotechCD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on…
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SouthernBiotech Mouse Anti-Mouse Ly-49I-BIOT
SouthernBiotechThe monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from…