25 mg, UN3077, Chemicals
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Pyrene-d10 98 atom % D
MilliporeSigmaMolecular Formula: C16D10 Molecular Weight: 212.31 Linear Structural Formula: C16D10 MDL Number: MFCD00084177 Melting Point: 145-148 C (lit.) Application: This product may be used as an analytical standard.
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SIGMA S15535 >=98% (HPLC), solid
MilliporeSigmaSynonym(s): 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1h-inden-2-yl)-piperazine Empirical Formula: C21H24N2O2 Linear Formula: C21H24N2O2 Formula Weight: 336.43 MDL Number: MFCD00911672 …
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ICI 192605
Cayman ChemicalICI 192605 is a potent antagonist of the thromboxane A2 receptor (TP) that blocks contraction of isolated guinea pig trachea induced by U-46619 (Item No. 16450; Kd = 0.398 nM). It is used to study the role of TP signaling in tissues and animals.
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SIGMA SR-46349 hemifumarate salt >=98% (HPLC)
MilliporeSigmaSynonym(s): 4-((3Z)-3-(2-Dimethylaminoethyl)oxyimino-3-(2-fluorophenyl)propen-1-yl)phenol hemifumarate salt; Eplivanserin hemifumarate salt; SR-46349B Empirical Formula: C19H21FN2O2 -+ 0.5 C4H4O4 Linear Formula: …
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Honokiol, 98+%
Thermo Scientific ChemicalsSynonym(s): 5,3'-Diallyl-2,4'-dihydroxybiphenyl Formula: C18H18O2 Formula weight: 266.34 Purity: 98+% CAS Number: 35354-74-6 UN Number: UN3077 Hazard Class: 9 Packing Group: III Harmonized Tariff Code: 2907.29 Hazard Statements: H318 Causes serious eye damage. …
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Cobimetinib
Cayman ChemicalA selective, orally available inhibitor of MEK1 (IC50 = 4.2 nM); induces differentiation and apoptosis in cancer cells lines.
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Dynasore
Cayman ChemicalA cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC50 = 15 μM); inhibits clathrin-dependent vesicle formation and endocytosis; can also augment the release of neurotransmitters and secreted cytokines.
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SIGMA Sal003 >=98% (HPLC)
MilliporeSigmaSynonym(s): (2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[[(4-chlorophenyl)amino]thioxomethyl]amino]ethyl]-2-propenamide; 3-Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide Empirical Formula: C18H15Cl4N3OS Linear…
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SIGMA Pyr3 >=98% (HPLC)
MilliporeSigmaSynonym(s): Ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate Empirical Formula: C16H11Cl3F3N3O3 Linear Formula: …
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SIGMA PF-429242 dihydrochloride >=98% (HPLC)
MilliporeSigmaSynonym(s): 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide dihydrochloride; PF 429242 dihydrochloride Empirical Formula: C25H35N3O2 -+ 2HCl Linear Formula: …
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SIGMA PS48 >=98% (HPLC)
MilliporeSigmaSynonym(s): 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid Empirical Formula: C17H15ClO2 Linear Formula: C17H15ClO2 Formula Weight: 286.75 MDL Number: MFCD17215962 Purity: ≥98% (HPLC) Storage: 2-8°C
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Magnolol
Cayman ChemicalA partial CB receptor agonist isolated from the bark of M. officinalis that has been used in Asian traditional medicine for the treatment of anxiety, sleep disorders, and allergic diseases; demonstrates selectivity for the peripheral CB2 receptor subtype (EC50 = 3.28 μM; Ki = 1.44…
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SIGMA PZ-II-029 >=98% (HPLC)
MilliporeSigmaSynonym(s): 2,5-Dihydro-7-methoxy-2-(4-methoxyphenyl)-3H-Pyrazolo[4,3-c]quinolin-3-one; 7-Methoxy-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one; PZII-029 Empirical Formula: C18H15N3O3 Linear Formula: …
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Efavirenz
Cayman ChemicalAn non-nucleoside reverse transcriptase inhibitor that prevents RNA plus-strand initiation (IC50 = 17 nM); also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing.
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SIGMA PD-156707 >=98% (HPLC)
MilliporeSigmaSynonym(s): α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt Empirical Formula: C28H25O9-+Na Linear Formula: C28H25O9-+Na Formula Weight: 528.48 …
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PiB =98% (HPLC)
MilliporeSigmaCAS Number: 64005-90-9 CAS Number: Empirical Formula (Hill Notation) C22H18N2O8 Molecular Weight: 438.39 MDL Number: MFCD00333607 PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to…
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Oxyphenbutazone
Cayman ChemicalAn NSAID that reduces edema in certain types of acute inflammation in animal models; a poor inhibitor of prostaglandin synthesis, but, like other NSAIDs, it inhibits OAT1 (Ki = 32 µM).
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G-1
Cayman ChemicalG-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 that binds with a Ki value of 11 nM. Competitive binding studies in endoplasmic reticulum α- (ERα-) and ERβ-expressing cells yielded Ki values for estradiol of 0.30 and 0.38 nM, respectively, with no substantial…
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Honokiol
Cayman ChemicalA natural product with diverse therapeutic effects, including acting as an anxiolytic in mice; inhibits NF-κB and PI3K/Akt signaling, preventing inflammation; interferes with angiogenesis while preventing tumor growth in vivo; scavenges superoxide and peroxyl radicals.
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SIGMA SNAP-94847 >=98% (HPLC)
MilliporeSigmaSynonym(s): N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methyl-propanamide Empirical Formula: C29H32F2N2O2 Linear Formula: C29H32F2N2O2 Formula…
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2-Methoxyestradiol
Cayman ChemicalA natural metabolite formed by CYP450-mediated hydroxylation followed by catechol-O-methyltransferase (COMT) methylation of estradiol; has anticancer agent activity as an angiogenesis inhibitor via the HIF-1α pathway; levels are significantly lower in women with severe pre-eclampsia.