25 g, NEW! Life Science
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Guaiacol
Cayman ChemicalGuaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of COX enzymes. It can therefore serve as a reducing co-substrate for COX reactions. The one-electron oxidation…
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Lecithin from Egg
MP BiomedicalsLecithin is the major membrane phospholipid in eukaryotic cells. In addition to being the major structural component of cellular membranes, it serves as a reservoir for several lipid messengers. It is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol,…
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Trimethoprim
Cayman ChemicalA synthetic antibiotic that inhibits dihydrofolate reductase (DHFR), with prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively); commonly used in combination with sulfamethoxazole to minimize acquired resistance.
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Syringic Acid
Cayman ChemicalA naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol; inhibits aldose reductase (IC50 = 213 µg/ml), proteasome activity, and cancer cell proliferation.
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Promethazine (hydrochloride)
Cayman ChemicalA first generation histamine H1 receptor antagonist (Ki = 2.6 nM) that also inhibits muscarinic acetylcholine receptors (Ki = 22 nM); penetrates the CNS, depressing central H1 receptor activity, which may relate to its sedative properties.
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5-Fluorouracil
Cayman ChemicalA pyrimadine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis; widely used to treat many gastrointestinal tract adenocarcinomas.
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ß-Estradiol
MP Biomedicalsβ-estradiol is a potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins leading to ovulation. β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). The pharmacology and HPLC determination of β-Estradiol…
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2-Hydroxypropyl-ß-cyclodextrin
Cayman ChemicalA cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.
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ß-Carotene
Cayman ChemicalA red/orange-colored fat-soluble terpenoid with antioxidant properties; can be cleaved to produce vitamin A and retinoic acid.
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Cellulose triacetate
Cayman ChemicalA polymer film used to manufacture high-performance membranes for dialysis, reverse osmosis, ion sensing, and separation; used in the production of photographic film and polarized film for liquid crystal displays.
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Phenylmethylsulfonyl fluoride
Cayman ChemicalA nonspecific, irreversible inhibitor of serine proteases and other enzymes, including acetylcholinesterase, palmityl coenzyme A deacylase, arylsulfatase A, chymotrypsin, and trypsin; also known to block anandamide metabolism, which produces CB effects in mice, including antinociception,…
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Adenosine triphosphate (ATP) disodium is clinically used to inhibit reperfusion injury after myocardial infarction during percutaneous coronary intervention; it also improves left ventricular function in clinical settings. ATP itself is a coenzyme and unit of cellular energy. ATP is required for…
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Bromhexine Hydrochloride
LKT LabsBromhexine is a synthetic derivative of vasicine that exhibits mucolytic and antioxidative activities. Bromhexine increases production of serous mucus, decreases mucus viscosity, and helps cilia transport mucus out of the lungs. Bromhexine is clinically used to treat respiratory disorders…
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Bromophenol Blue
Cayman ChemicalCommonly used as a pH indicator, a color marker in agarose or polyacrylamide gel electrophoresis, and a dye to detect proteins and nucleic acids (absorbance at 610 nm), particularly when staining living tissues.
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Bromelain
Cayman ChemicalA mixture of proteolytic enzymes derived from the stem and fruit of pineapple plants; studied for a number of potential beneficial effects including anti-inflammatory, anti-thrombotic, fibrinolytic, and anti-cancer functions.
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Tranexamic Acid
Cayman ChemicalAn inhibitor of fibrinolysis that blocks the interaction of plasmin with fibrin (IC50 = 3.1 µM).
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Chlorzoxazone
Cayman ChemicalA benzoxazolone derivative that causes skeletal muscle relaxation and blocks spasticity in clinical studies; enhances KCa2.2 and KCa3.1 channels (EC50s = 87 and 98 µM, respectively); urinary excretion of its 6-hydroxy metabolite is often used as a probe of CYP2E1 activity in…
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Propylthiouracil
Cayman ChemicalA derivative of thiouracil which has long been used to correct hyperthyroidism; also used as a genetic marker for taste, since only some people detect it as a bitter taste.
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DL-a-Lipoic Acid
Cayman ChemicalDL-α-lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle, and acts as a general antioxidant.{12280,12281,12322} DL-α-lipoic acid can act as a direct radical…
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Icariin
Cayman ChemicalAn inhibitor of human recombinant PDE5 (IC50 = 5.9 µM); used to treat erectile dysfunction and has been shown to have anti-cancer and antioxidant activity; induces differentiation of cardiomyocytes and increases the proliferation and differentiation of cultured human osteoblasts.
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Cimetidine
LKT LabsCimetidine is an antihistamine that inhibits H2 histamine receptors, exhibiting antacid and anticancer chemotherapeutic activities. Cimetidine inhibits catalase activity and also acts as an antagonist at androgen receptors. Cimetidine increases the efficacy of chemotherapeutic compounds when…
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Taurocholic Acid (sodium salt)
Cayman ChemicalA bile salt formed in the liver by conjugation of cholic acid with taurine that can be used to solubilize lipids and membrane-bound proteins.
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trans-2-Decenoic Acid
Cayman ChemicalAn unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees; isolated in conjunction with 10-HDA (Item No. 10976) and both demonstrate weak estrogenic activity, inhibiting binding of 17β-estradiol (Item No. ISO60155) to estrogen…
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Glycyrrhizic Acid (ammonium salt)
Cayman ChemicalA natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions.
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(±)-Jasmonic Acid methyl ester
Cayman ChemicalA mixture of trans (3R/7R and 3S/7S) isomers; induces the synthesis of proteinase inhibitors in plant leaves; in cancer cells, suppresses proliferation and induces apoptosis; inhibits hexokinase that is bound to mitochondria; methyl jasmonate derivatives also have potential as anti-inflammatory agents.
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ß-D-Glucose
Cayman ChemicalOne of two cyclic forms of D-glucose that is the monomer unit in cellulose.
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Acridine Orange
Cayman ChemicalA cell-permeable, fluorescent dye that accumulates in acidic organelles in a pH-dependent manner and is used for autophagy detection and cell cycle determination; emits green fluorescence (ex. max: 502 nm; ,em. max: 525 nm) at neutral pH or when bound to dsDNA and red fluorescence (ex. max: 460 nm;…
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IPTG (dioxane free)
Cayman ChemicalInduces protein expression where the gene is under the control of the lac operator by triggering transcription of the lac operon in cloning procedures.