EPA is an ω-3 fatty acid abundantly available in marine organisms. It is a poor substrate for COX-1. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.

ALA is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation.

A plant growth regulator involved in the signaling mechanisms for a variety of conditions including plant defense, wound healing, tuberization, fruit ripening, and senescence.

An essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain; constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes; dietary supplementation via fish oil inhibits the progression of atherosclerosis and delays…

Keystone essential fatty acid that is converted by COX, LO, and epoxygenase enzymes into more than 150 potent metabolites in species ranging from fungi to plants to mammals.

13(Z)-Docosenoic acid is a 22-carbon monounsaturated fatty acid. It is found predominantly in canola oil. 13(Z)-Docosenoic acid is metabolized to oleic acid in vivo. Diets rich in 13(Z)-docosenoic acid were shown to cause heart lipidosis in experimental animals. The C-1 amide of docosenoic acid has…

An uncommon, naturally occurring PUFA, inhibits the binding of [3H]-LTB4 to porcine neutrophil membranes with a Ki value of 3 µM.

A monounsaturated long chain fatty acid with potential antitumor and p53 inhibitory activity.

Linoleic acid is a PUFA prevalent in the western diet. The peroxide free linoleic acid is protected from autoxidation by the antioxidant BHT (2,6-Di-tert-butyl-4-hydroxytoluene). Linoleic acid is also available without BHT (Item No. 90150).

EPA is an ω-3 fatty acid abundantly available in marine organisms. Peroxide free EPA has been chromatographed under scrupulously oxygen free conditions to insure the removal of all contaminating fatty acid peroxides. The peroxide free EPA is protected from autoxidation by the antioxidant BHT…

A 15-carbon, long-chain fatty acid that contains an alkene functional group on the terminal carbon of its aliphatic tail.

γ-Linolenic acid is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. γ-Linolenic acid produces 53%…

PUFAs are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Methyl GLA is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets and dietary supplements. GLA is an…

An esterified version of GLA which is less water soluble but more amenable for the formulation of GLA-containing diets.

A cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions; used in the composition of lipospomes formulated as SNALPs.

A minor constituent of ruminant fats with potential antitumor activity.

A polyunsaturated fatty alcohol produced by the reduction of linoleic acid.

A fluorinated building block for the synthesis of various pharmaceutical amides.

Linoelaidic acid is the all-trans fatty acid homolog of linoleic acid. Trans-fatty acids are generally not detected in raw food oils, but constitute up to 25% of the unsaturated fat in partially hydrogenated oils.

Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Arachidonic acid oxidizes spontaneously on exposure to room air, yielding a complex mixture of fatty acid peroxides. Peroxide-free arachidonic acid is obtained after removal of the…