(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. It contains equal amounts of 5(S)-HETE and 5(R)-HETE. (±)5-HETE induces the aggregation of isolated neutrophils with an IC₅₀ value of 200 nM.

The Recombinant Human protein IFN Gamma has a gene ID of 3458. The proteins are lyophilized and are reconstituted with PBS containing at least 0.1% carrier protein. The calculated M.W. is 16.8kDa. The proteins are expressed in a yeast system and endotoxin free.

An EpEDE acid formed from DGLA, either by a strong oxidizing agent or by cytochrome P450 epoxygenases; biological properties are poorly understood.

A cyanobacterial toxin that targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 µM, respectively), inhibits uridine monophosphate synthase complex activity (Ki = 10 µM), and induces DNA damage.

11-trans LTD4 is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging…

A proposed anti-inflammatory EPA metabolite that has been shown to promote inflammatory resolution in numerous disease models, including experimental colitis, asthma, atherosclerosis, type 2 diabetes, and HSV-1-induced stromal keratitis.

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 µM); demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently inhibits angiogenesis and tumor growth in in vitro assays.

An internal standard for the quantification of PGF2α by GC- or LC-MS.

Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. iPF2α-VI is one of dozens of possible stereo- and…

Anti-CD19 is useful for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

(±)12-HpETE is one of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid (Item No. 90010) and consists of an equal mixture of the R and S isomers. Reduction of the hydroperoxide yields the more stable hydroxyl fatty acid (±)12-HETE (Item…

A dehydration product of tetranor-PGEM that can be measured as a surrogate for tetranor-PGEM levels in urine.

Differs from the major microcystin variant LR with the substitution of alanine in place of the arginine; inhibits both PP1C and PP2A with an IC50 value of 0.3 nM.

A DHA-derived product first identified in mouse inflammatory exudates; reduces neutrophil infiltration in vivo in both mouse peritonitis and dermal inflammation; enhances macrophage phagocytosis and efferocytosis.

Synonym(s): FGF2; bFGF CAS No.: 106096-93-9 Purity: ≥97% (SDS-PAGE) Application: FGF-2 is required for the maintenance of human embryonic stem cells in culture, and various other stem cell lines such as mesenchymal stem (stroma) cells (MSC). General description: FGF2 is found in…

One of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.

An analog of (±)14(15)-EpEDE with greater lipid solubility than the free base.

A bioactive macrolide derived from sponges that binds monomeric actin, preventing actin polymerization both in vitro (Kd = 0.2 μM) and in cells (0.5 μM).

Synonyms: bFGF; FGB-b; FGF-2; HBGF-2; HBGH-2; Prostatropin Purity: >=97% (SDS-PAGE) Storage: -20C UNSPSC Code: 12352200 General description: Fibroblast Growth Factor-Basic (FGF-Basic) is a potent mitogenic agent for a wide variety of mesoderm-derived cells including BALB/c 3T3…

17-trans PGE3 is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids. There are no published reports on the biological activity of this compound.

A potential metabolite of PGD2, presumably produced from the known metabolite 13,14-dihydro-15-keto PGD2.

A DHA epoxygenase metabolite found in rat brain and spinal cord that acts as a preferred substrate for sEH (Km = 3.2 µM); demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently inhibits angiogenesis and tumor growth in in vitro assays.

An internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-MS.

A major metabolite of PGD2 found in human and mouse urine at levels of approximately 1.5 and 8.1 ng/mg creatinine, respectively.

An internal standard for quantification of 13,14-dihydro-15 (R,S)-hydroxy-16,16-difluoro-Prostaglandin E1, a metabolite of a bicyclic PGE1 derivative used in the treatment of chronic constipation, by GC- or LC-mass spectrometry (MS).

The recombinant mouse protein IL-10 has a gene ID of 16153. These proteins are lyophilized and are reconstituted with sterile PBS containing at least 0.1% carrier protein. The calculated M.W. is 18.8kDa. The proteins are in a yeast system and endotoxin free.

A high quality mouse reference RNA product, treated to ensure undetectable DNA levels. Offers greater consistency than RNA references derived from tissue sources alone Provides the maximum representation of low, medium, and high abundant gene transcripts. Manufactured at industrial scale…

Biotin Mouse TrueBlot® ULTRA is ideal for use in protocols involving immunoblotting of immunoprecipitated proteins. Biotin Mouse TrueBlot® ULTRA preferentially detects the non-reduced form of mouse IgG (IgG1, IgG2a, IgG2b, IgG3) over the reduced, SDS-denatured form of IgG. To achieve best results…

The racemic version of a CYP450 metabolite of arachidonic acid that dose-dependently stimulates vasodilation of the rabbit kidney.

An aspirin-triggered lipoxin that inhibits LTB4-induced chemotaxis, adherence, and transmigration of the neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.

The recombinant mouse protein IL-2 has a gene ID of 16183. These proteins are lyophilized and are reconstituted with sterile PBS containing at least 0.1% carrier protein. The calculated M.W. is 17.6kDa. The proteins are in a yeast system and endotoxin free.