1 mg
-
Bafetinib
Cayman ChemicalA Bcr-Abl kinase inhibitor (IC50 = 5.8 nM) that is 25- to 55-fold more potent than imatinib in vitro and ≥10-fold more potent in vivo; inhibits 12 out of the 13 most frequent imatinib-resistant Bcr-Abl point mutations, but not the T315I mutation; also targets the Src family kinase Lyn…
-
Anti-HUMAN TRANSFERRIN (RABBIT) Antibody, 1mg, Liquid (sterile filtered)
Rockland Immunochemicals IncAnti-Human transferrin has been assayed against 1.0 µg of Human Transferrin in a standard sandwich ELISA using Peroxidase conjugated Affinity Purified Donkey anti-Rabbit IgG [H&L] MX code #611-703-127 and TMB as a substrate for 30 minutes at room temperature. A working dilution of 1:12,000…
-
ML-7 (hydrochloride)
Cayman ChemicalInhibits smooth MLCK (Ki = 0.3 µM) 10-fold more potently than its parent compound ML-9.
-
Corning® Collagen
CorningCorning extracellular matrices (ECMs) enable researchers to mimic in vivo environments for 2D and 3D cell culture applications. Corning offers a broad range of collagen types that are derived from multiple species. These collagens have been used to culture a variety of cell types to promote…
-
Calcein AM
Cayman ChemicalA cell-permeable dye that is cleaved by intracellular esterases, leaving membrane-impermeant calcein, a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively.
-
Actin, from rabbit muscle
Thermo Scientific ChemicalsCAS Number: 51005-14-2 Harmonized Tariff Code: 3504.00
-
Cy™3 AffiniPure F(ab')2 Fragment Goat Anti-Mouse IgG, Fcy Fragment Specific
Jackson ImmunoresearchF(ab')2 fragment antibodies are generated by pepsin digestion of whole IgG antibodies to remove most of the Fc region while leaving some of the hinge region. F(ab')2 fragments have two antigen-binding Fab portions linked together by disulfide bonds and therefore they are divalent. The…
-
U-73122
Cayman ChemicalAn inhibitor of PLC-dependent processes by an undefined mechanism; inhibits platelet aggregation induced by collagen or thrombin with IC50 values of 0.6 and 5 µM, respectively.
-
Anti-FLUORESCEIN (GOAT) Antibody Alkaline Phosphatase Conjugated, 1mg, Liquid …
Rockland Immunochemicals IncAnti-Fluorescein Antibody Alkaline Phosphatase Conjugated is suitable for immunoblotting (western or dot blot), ELISA, in situ hybridization and immunohistochemistry as well as other phosphatase-antibody based enzymatic assays requiring lot-to-lot consistency.
-
BPIQ-I
Cayman ChemicalA quinazoline that inhibits the tyrosine kinase activity of EGFR (IC50 = 0.025 nM); inhibits the growth of SKOV3 and MDA-468 tumor cell lines (EC50s = 6.5 and 30 µM, respectively).
-
Anti-RABBIT IgG (H&L) (GUINEA PIG) Antibody Fluorescein Conjugated (Min X Hu, Gt…
Rockland Immunochemicals IncThis product is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various commercial platforms.
-
Anti-Human IL-1 Receptor Antagonist (RABBIT) Antibody
Rockland Immunochemicals IncThis IgG fraction antibody of anti-Human IL-1 Receptor Antagonist has been tested for use in neutralizations, ELISA, radioimmunoassays, western blotting, immunohistochemistry and flow cytometry. Reactivity in other immunoassays is unknown. This product has been assayed by immunoblot using HRP…
-
Anti-RABBIT IgG (H&L) (MOUSE) Antibody Rhodamine Conjugated (Min X Hu, Gt, Ms…
Rockland Immunochemicals IncMouse Anti-Rabbit IgG Rhodamine conjugate is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various commercial platforms.
-
3'-Azido-3'-deoxythymidine ß-D-glucuronide (sodium salt)
Cayman ChemicalA metabolite of the nucleoside reverse transcriptase inhibitor, zidovudine, formed by direct conjugation by UGT2B7.
-
Skimmin >=90% (LC/MS-UV)
MilliporeSigmaNatural product derived from plant source. Synonyms: 7-Hydroxycoumarin-7-glucoside; Umbelliferone glucoside Molecular Formula: C15H16O8 Molecular Weight: 324.28 Linear Structural Formula: C15H16O8 MDL Number: MFCD00017710 Purity: >=90% (LC/MS-UV) Storage: -20C Biochem…
-
RQ-00203078
Cayman ChemicalA selective TRPM8 antagonist (IC50s = 8.3 and 5.8 nM in human and rat, respectively); attenuates icilin-induced wet-dog shakes in rats (ED50 = 0.65 mg/kg); reduces HSC3 and HSC4 oral squamous carcinoma cell migration and invasion in vitro.
-
5-chloro Hydrochlorothiazide
Cayman ChemicalA derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.
-
SB-525334
Cayman ChemicalA potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM); blocks TGF-β1-induced phosphorylation and nuclear translocation of SMAD2/3 as well as TGF-β1-directed gene expression; effective in vivo, preventing the development of fibrosis in animals.
-
Anti-MOUSE IgG1 (Gamma 1 chain) (GOAT) Antibody Rhodamine Conjugated (Min Cross…
Rockland Immunochemicals IncMouse IgG1 Antibody Rhodamine Conjugated is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various commercial platforms.
-
THZ1
Cayman ChemicalA covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell lineage-specific transcription factors.
-
PP2
Cayman ChemicalA potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases: p56lck (IC50 = 4 nM), p59fynT (IC50 = 5 nM), Hck (IC50 = 5 nM).
-
Anti-CHICKEN IgG F(c) (RABBIT) Antibody Alkaline Phosphatase Conjugated, 1mg,…
Rockland Immunochemicals IncThis product has been assayed against 1.0 ug of Chicken IgG in a standard capture ELISA using pNPP p-nitrophenyl phosphate code # NPP-10 as a substrate for 30 minutes at room temperature. A working dilution of 1:2,000 to 1:9,000 of the reconstitution concentration is suggested for this product.
-
11ß-Prostaglandin F2a Ethanolamide
Cayman Chemical11β-PGF2α-EA is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues. AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of…
-
Anti-HUMAN IgG [H&L] (GOAT) Antibody CY3.5 Conjugated Min X Bv Ch Gt GP Ham Hs…
Rockland Immunochemicals IncThis product is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various commercial platforms.
-
BzATP (ammonium salt)
Cayman ChemicalAn activator of the P2X receptors that exhibits 5-30-fold greater potency at the P2X7 receptor than ATP; activates the human, rat, and mouse receptors with EC50 values of 0.7, 3.6, and 285 μM, respectively.
-
L-902,688
Cayman ChemicalA potent and selective agonist of the human PGE2 receptor, EP4 with a Ki value of 0.38 nM and an EC50 value of 0.6 nM; induces thermal hyperalgesia when injected into guinea pig forepaw and increases vasodilation of human pulmonary vein.
-
Anti-GOLDEN SYRIAN HAMSTER IgG (H&L) (GOAT) Antibody Alkaline Phosphatase…
Rockland Immunochemicals IncAnti-Golden Syrian Hamster IgG Alk Phos conjugate is suitable for immunoblotting (western or dot blot), ELISA, immunoelectron microscopy and immunohistochemistry as well as other antibody-based enzymatic assays requiring lot-to-lot consistency.
-
Fab Anti-GOAT IgG (H&L) (DONKEY) Antibody Peroxidase Conjugated, 1mg,…
Rockland Immunochemicals IncAntibody Anti-Goat IgG (H&L) peroxidase conjugated is suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunohistochemistry as well as other peroxidase-antibody based enzymatic assays requiring extremely low background levels, lot-to-lot…
-
KP372-1
Cayman ChemicalA specific Akt inhibitor that has been shown to inhibit proliferation and to induce apoptosis of thyroid cancer cells (IC50 = 30-60 nM in vitro); inhibits Akt, PDK1, and FLT3 in acute myelogenous leukemia cells, decreasing the colony-forming ability of these cells (IC50…
-
BIO
Cayman ChemicalA cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3α/β (IC50 = 5 nM); inhibition of GSK activates the Wnt-signaling pathway and sustains pluripotency in human and mouse ESCs; maintains…
-
Cannabidivarinic Acid (CRM)
Cayman ChemicalA certified reference material categorized as a phytocannabinoid; has been found in strains of Cannabis; intended for research and forensic applications
-
8-iso Prostaglandin F1ß
Cayman Chemical8-iso PGF1β is a potential autoxidation product of DGLA. There are no published reports on its isolation from any biological source or on its biological activity.