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1 g, 54-36-4

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Metyrapone

Cayman Chemical

Blocks cortisol synthesis by inhibiting steroid 11β-hydroxylase in adrenal cortex (IC₅₀ = 7.8 μM); also binds with high affinity to CYP450 in hepatic microsomes and induces rat hepatic CYP1A1 and CYP3A gene expression.

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