10 g, Chemicals, Bottle, Glass, Clear
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Luminol
Cayman ChemicalA cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation; HRP combined with H2O2 causes luminescent peroxidation of luminol; can also be oxidized, and chemiluminesce, by compounds containing iron, copper, gold, and cyanide.
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Tamoxifen
Cayman ChemicalA selective estrogen receptor (ER) modulator; an ER antagonist in breast tissue, effective in treating early breast cancer; an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues.
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Griseofulvin
Cayman ChemicalA natural bacterial product used, in certain formulations, as an oral antibiotic for fungal infections of the skin; alters microtubule dynamics, resulting in metaphase arrest.
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Resazurin (sodium salt)
Cayman ChemicalA blue non-fluorescent dye that is used as an oxidation-reduction indicator in cell viability assays in a variety of cells; can be reduced to the highly red-fluorescent product resorufin (excitation: 530-540 nm; emission: 585-595 nm) and used as a quantifiable detection agent in enzyme activity or…
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Glycyrrhizic Acid (ammonium salt)
Cayman ChemicalA natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions.
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Taurocholic Acid (sodium salt)
Cayman ChemicalA bile salt formed in the liver by conjugation of cholic acid with taurine that can be used to solubilize lipids and membrane-bound proteins.
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Tamoxifen (citrate)
Cayman ChemicalA selective estrogen receptor (ER) modulator used as adjuvant therapy for estrogen-dependent breast cancer; increases ER activity in bone, uterus, and the cardiovasculature system as it decreases ER activity in breast tissues; metabolized by CYP450 enzymes to active metabolites; alters cholesterol…
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2-Thenoyltrifluoroacetone
Cayman ChemicalAn inhibitor of respiration in animals and bacteria; binds at the quinone reduction site of succinate:ubiquinone oxidoreductase (SQR; Complex II) in animals, preventing ubiquinone from binding; inhibits NADH fumarate reductase in bacteria; inhibits photosystem II in plants.
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Ceftazidime (hydrate)
Cayman ChemicalA broad-spectrum β-lactam antibiotic used for parenteral administration.
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N-Octyl-ß-D-thioglucopyranoside
Cayman ChemicalA low molecular weight nonionic detergent that is commonly used for cell lysis and non-denaturing protein solubilization.
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L-Glutathione, reduced
Cayman ChemicalGSH is a tripeptide (γ-glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of…
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Sodium Hydrogen Sulfide (hydrate)
Cayman ChemicalAn H2S donor commonly used in cellular and whole animal experimental systems.
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Palmitic Acid
Cayman ChemicalA common 16-carbon saturated fatty acid that represents 10-20% of the normal human dietary fat intake.
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Promethazine (hydrochloride)
Cayman ChemicalA first generation histamine H1 receptor antagonist (Ki = 2.6 nM) that also inhibits muscarinic acetylcholine receptors (Ki = 22 nM); penetrates the CNS, depressing central H1 receptor activity, which may relate to its sedative properties.
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trans-2-Decenoic Acid
Cayman ChemicalAn unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees; isolated in conjunction with 10-HDA (Item No. 10976) and both demonstrate weak estrogenic activity, inhibiting binding of 17β-estradiol (Item No. ISO60155) to estrogen…
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2-Hydroxypropyl-ß-cyclodextrin
Cayman ChemicalA cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.
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Acridine Orange
Cayman ChemicalA cell-permeable, fluorescent dye that accumulates in acidic organelles in a pH-dependent manner and is used for autophagy detection and cell cycle determination; emits green fluorescence (ex. max: 502 nm; ,em. max: 525 nm) at neutral pH or when bound to dsDNA and red fluorescence (ex. max: 460 nm;…
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Bromelain
Cayman ChemicalA mixture of proteolytic enzymes derived from the stem and fruit of pineapple plants; studied for a number of potential beneficial effects including anti-inflammatory, anti-thrombotic, fibrinolytic, and anti-cancer functions.
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5-Fluorouracil
Cayman ChemicalA pyrimadine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis; widely used to treat many gastrointestinal tract adenocarcinomas.
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Xylazine
Cayman ChemicalAn agonist of α2 adrenergic receptors (Ki = 194 nM); used for sedation, anesthesia, and analgesia in non-human mammals.
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DL-a-Lipoic Acid
Cayman ChemicalDL-α-lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle, and acts as a general antioxidant.{12280,12281,12322} DL-α-lipoic acid can act as a direct radical…
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Fluconazole
Cayman ChemicalA triazole antifungal agent that is effective against most Candida strains.
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4-Aminopyridine
Cayman ChemicalA non-selective blocker of voltage-dependent K+-channels (Kv channels) that has greatest potency at Kv1 and Kv3 family members (IC50s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively); also blocks Kv2 and Kv4 subunits at millimolar concentrations.
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Trimethoprim
Cayman ChemicalA synthetic antibiotic that inhibits dihydrofolate reductase (DHFR), with prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively); commonly used in combination with sulfamethoxazole to minimize acquired resistance.
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Vitamin D2
Cayman ChemicalProduced in fungi, including yeast, and invertebrates from ergosterol in response to ultraviolet radiation; metabolized first to 25-hydroxyvitamin D2 and subsequently to the active 1,25-dihydroxyvitamin D2.
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2-cyano-Pyrimidine
Cayman ChemicalCathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis. 2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and derivatives are being studied for the treatment of osteoporosis.…
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Probucol
Cayman ChemicalA potent antioxidant that inhibits the oxidation of cholesterol in LDL and HDL by impairing the translocation of ABCA1 from intracellular compartments to the plasma membrane.
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Spermidine
Cayman ChemicalA natural polyamine that plays diverse roles in signal transduction and metabolism; involved in growth, development, and stress responses in plants.
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(+)-Pilocarpine (hydrochloride)
Cayman ChemicalA muscarinic M1 and M2 mACh receptor agonist (pKB = 5 and 3.7, respectively) that is typically used as an animal model for temporal lobe epilepsy.
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Icariin
Cayman ChemicalAn inhibitor of human recombinant PDE5 (IC50 = 5.9 µM); used to treat erectile dysfunction and has been shown to have anti-cancer and antioxidant activity; induces differentiation of cardiomyocytes and increases the proliferation and differentiation of cultured human osteoblasts.
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Fenbendazole
Cayman ChemicalA broad-spectrum benzimidazole anthelmintic that is active against gastrointestinal parasites (IC50 = 0.30 µM against Giardia in vitro) by targeting tubulin; activates HIF-1α, abrogating oxidative stress-induced death in primary neurons in vitro.
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Spectinomycin (hydrochloride hydrate)
Cayman ChemicalAn aminocyclitol antibiotic active against Gram-negative and Gram-positive bacteria; inhibits protein synthesis by binding to the 30S ribosomal subunit and interfering with peptidyl tRNA translocation.