Cayman Chemical, 1 g, NEW! Life Science
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4-Pyrimidinecarboxaldehyde, dimethyl acetal
Cayman Chemical4-Pyrimidinecarboxaldehyde, dimethyl acetal is a synthetic intermediate useful for pharmaceutical synthesis.
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L-Leucine 4-methoxy-ß-naphthylamide (hydrochloride)
Cayman ChemicalA cell-permeable substrate for aminopeptidase M and leucine aminopeptidase that was developed for intracellular analysis of protease activities.
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L-(-)-Fucose
Cayman ChemicalA deoxyhexose monosaccharide found on N- and O-linked glycans and glycolipids that exists either as a terminal modification of glycan structures or serves as a point of attachment for adding other sugars; plays a role in A and B blood group antigen substructure determination, selectin-mediated…
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Trolox
Cayman ChemicalA cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties; commonly used as a standard or positive control in antioxidant assays.
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Cetirizine (hydrochloride)
Cayman ChemicalA second generation antihistamine that acts as a selective histamine H1 receptor antagonist (pKi = 8).
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3,4,6-Tri-O-benzyl-ß-D-Mannopyranose 1,2-(methyl orthoacetate)
Cayman ChemicalA synthetic intermediate used in glycosylation reactions.
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Bupivacaine
Cayman ChemicalAn amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential; inhibits the uptake of dopamine in striatal synaptosomes by 47% at 100 µM.
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3-Pyrimidin-2-yl-Propionic Acid
Cayman Chemical3-Pyrimidin-2-yl-Propionic Acid is a synthetic intermediate useful for pharmaceutical synthesis.
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Kynurenic Acid
Cayman ChemicalA metabolite of tryptophan that has pronounced effects on neuronal signaling; broadly antagonizes ionotopic glutamate receptors; has potent effects at glutamate receptor subunit ζ-1 (Ki = 5.4 µM), GPR35 (EC50 = 39 µM), aryl hydrocarbon receptor (EC50 = 300…
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N-acetyl-D-Glucosamine
Cayman ChemicalA monosaccharide derivative of glucose that is released by the action of O-GlcNAcase, in mammalian systems, from proteins that have been post-translationally modified with O-GlcNAc; also is the monomeric unit of chitin, which is found in fungi and many inverebrates, including crustaceans, insects,…
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Tamoxifen
Cayman ChemicalA selective estrogen receptor (ER) modulator; an ER antagonist in breast tissue, effective in treating early breast cancer; an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues.
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DL-a-Lipoic Acid
Cayman ChemicalDL-α-lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle, and acts as a general antioxidant.{12280,12281,12322} DL-α-lipoic acid can act as a direct radical…
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Metformin (hydrochloride)
Cayman ChemicalA biguanide derivative used to lower blood glucose concentrations in patients with non-insulin-dependent diabetes mellitus; 50-400 mg/kg body weight inhibits complex 1 of the mitochondrial respiratory-chain and induces AMP-activated protein kinase-dependent signaling in B6-Lepob/ob mice.
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Clinafloxacin (hydrochloride)
Cayman ChemicalA fluoroquinolone antibiotic that displays broad spectrum antibacterial activity by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).
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L-Leucyl-L-Leucine methyl ester (hydrochloride)
Cayman ChemicalA lysosomal condensation product that selectively eliminates dipeptidyl peptidase I-expressing immune cells, including cytotoxic T cells and natural killer cells.
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5-Fluorocytosine
Cayman ChemicalAn antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil, a cytotoxic drug that inhibits viral infections and has cytotoxic effects on cancer cells.
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Aztreonam
Cayman ChemicalA monobactam antibiotic that is effective against Gram-negative bacteria but inactive against Gram-positive bacteria.
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2-phenyl-3-methyl-Quinoxaline
Cayman ChemicalA synthetic intermediate useful for pharmaceutical synthesis.
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Spermidine
Cayman ChemicalA natural polyamine that plays diverse roles in signal transduction and metabolism; involved in growth, development, and stress responses in plants.
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Xylazine
Cayman ChemicalAn agonist of α2 adrenergic receptors (Ki = 194 nM); used for sedation, anesthesia, and analgesia in non-human mammals.
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X-Gal
Cayman ChemicalA cell-permeable, chromogenic substrate for β-galactosidase used in histochemical and molecular biology applications, including detection of lacZ activity in cells and tissues.
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Quetiapine (hemifumarate)
Cayman ChemicalAn atypical, second generation antipsychotic compound that has effects at multiple receptors; antagonizes dopamine D1, D2, and D3 receptors, serotonin 5-HT1A, 5-HT2A, and 5-HT7 receptors, and α1A, α1B, and α2C adrenergic receptors.
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Sodium 4-Phenylbutyrate
Cayman ChemicalA chemical chaperone that rescues the trafficking of misfolded proteins and weakly blocks HDAC activity (IC50 = 0.4 mM), leading to cell cycle arrest, differentiation, and/or apoptosis of various tumors.
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SAHA
Cayman ChemicalAn HDAC inhibitor of class I and class II HDACs at around 50 nM; arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.
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ß-D-Glucosamine Pentaacetate
Cayman ChemicalAn N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production.
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Artemisinin
Cayman ChemicalA natural product which effectively kills malarial parasites of the genus Plasmodium (IC50 = 4.0 nM); also used against a wide range of trematodes, including Schistosoma; has potential applications in certain types of cancer and inflammatory conditions.
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Icariin
Cayman ChemicalAn inhibitor of human recombinant PDE5 (IC50 = 5.9 µM); used to treat erectile dysfunction and has been shown to have anti-cancer and antioxidant activity; induces differentiation of cardiomyocytes and increases the proliferation and differentiation of cultured human osteoblasts.
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Fluconazole
Cayman ChemicalA triazole antifungal agent that is effective against most Candida strains.
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4-Methylumbelliferyl-ß-D-Glucuronide (hydrate)
Cayman ChemicalA fluorogenic substrate of β-glucuronidase that upon cleavage yields a blue fluorescent end product that can be monitored by UV light; typically used in the GUS reporter system for fluorescent detection of β-glucuronidase gene expression in E. coli and transformed plants.
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D-Luciferin (potassium salt)
Cayman ChemicalA chemiluminescent substrate of firefly luciferase which produces light upon oxidative decarboxylation in the presence of ATP.
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NADP+ (sodium salt hydrate)
Cayman ChemicalThe oxidized form of NADPH; serves as a cofactor in various biological reactions.