Cayman Chemical, UN1231, 50 µg
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4-hydroxy Nonenal-d3
Cayman Chemical4-hydroxy Nonenal-d3 contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-hydroxy nonenal (4-HNE) by GC- or LC-mass spectrometry.
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13,14-dihydro-15-keto Prostaglandin F2a-d4
Cayman Chemical13,14-dihydro-15-keto PGF2α-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGF2α by GC- or LC-MS.
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Prostaglandin A3
Cayman ChemicalCyclooxygenase metabolism of EPA to produce PGE3 has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. PGA3 is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and EP4 receptors with…
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Latanoprost-d4
Cayman ChemicalAn internal standard for the quantification of Latanoprost by GC- or LC-MS.
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11-dehydro-2,3-dinor Thromboxane B2
Cayman Chemical11-dehydro-2,3-dinor TXB2 has been identified as a TXB2 metabolite in human urine by GC/MS. The relative abundance is only about one-tenth that of 11-dehydro TXB2, making it unlikely that 11-dehydro-2,3-dinor TXB2 will be used widely as an index of thromboxane synthesis.
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Prostaglandin F2a Ethanolamide-d4
Cayman ChemicalAn internal standard for the quantification of PGF2α-EA by GC- or LC-MS.
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6-keto Prostaglandin F1a-d4
Cayman ChemicalPGF1α-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGF1α by GC- or LC-mass spectrometry.
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Prostaglandin E1-d4
Cayman ChemicalAn internal standard for the quantification of PGE1 by GC- or LC-MS.
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PGDM
Cayman ChemicalA major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization; used as a biomarker to assess endogenous production of PGD2.
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4-oxo 2-Nonenal-d3
Cayman Chemical4-ONE-d3 contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-ONE by GC- or LC-MS.
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tetranor-PGDM-d6
Cayman ChemicalAn internal standard for the quantification of tetranor-PGDM by GC- or LC-MS.
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Prostaglandin D3
Cayman ChemicalPGD3 is produced by the metabolism of EPA via the COX pathway. It is equipotent to PGD2 in decreasing systemic blood pressure in rats and in decreasing intraocular pressure in rabbits. However, it is 3-5 times more potent than PGD2 in the inhibition of ADP-induced human platelet aggregation.
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Prostaglandin E2-d9
Cayman ChemicalAn internal standard for the quantification of PGE2 by GC- or LC-MS.
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Prostaglandin F3a
Cayman ChemicalPGF3α is a COX product of EPA. The biosynthesis of PGF3α from EPA was demonstrated in vitro in human and rabbit ocular tissues. It has only 25% affinity at the ovine luteal FP receptor compared to PGF2α.
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(±)5(6)-EET-d11
Cayman ChemicalAn internal standard for the quantification of (±)5(6)-EET by GC- or LC-MS.
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U-46619 Glycine methyl ester
Cayman ChemicalAn analog of U-46619, a stable analog of the endoperoxide PGH2 in the arachidonic acid metabolic pathway.
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2,3-dinor Thromboxane B1
Cayman ChemicalTXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.{1410} In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2.{12600,12599} However in human urine, only trace…
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8-iso-13,14-dihydro-15-keto Prostaglandin F2a
Cayman ChemicalA metabolite of 8-iso PGF2α in rabbits, monkeys, and humans.
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tetranor-PGEM-d6
Cayman ChemicalAn internal standard for the quantification of tetranor PGEM by GC- or LC-MS.
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tetranor-PGDM lactone-d6
Cayman ChemicalAn internal standard for the quantification of tetranor-PGDM lactone by GC- or LC-MS.
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Prostaglandin E2-d4
Cayman ChemicalAn internal standard for the quantification of PGE2 by GC- or LC-MS.
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20-hydroxy Prostaglandin E2
Cayman ChemicalA CYP450 ω-oxidation metabolite of PGE2 that preceeds β-oxidation and the loss of up to four carbons from the lower side chain of PGE2.
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(±)9(10)-DiHOME-d4
Cayman Chemical(±)9(10)-DiHOME-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of (±)9(10)-DiHOME by GC- or LC-MS.
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8,12-iso-iPF2a-VI-1,5-lactone
Cayman ChemicalA racemic mixture of the lactone form of the free acid, 8,12-iso- iPF2α-VI; the free acid is the most abundant F2-iP2 regioisomer measured in the urine of rats treated to induce lipid peroxidation; used as a biomarker for oxidative stress.
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Latanoprost (free acid)-d4
Cayman ChemicalAn internal standard for the quantification of latanoprost (free acid) by GC- or LC-MS.
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2,3-dinor Thromboxane B2
Cayman ChemicalAn endogenous CB neurotransmitter that binds to both CB1 and CB2 receptors.
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15-deoxy-?12,14-Prostaglandin J2-d4
Cayman Chemical15-deoxy-.DELTA.12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-.DELTA.12,14-PGJ2 by GC- or LC-mass spectrometry.
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2,3-dinor-8-iso Prostaglandin F2a
Cayman ChemicalA metabolite of 8-iso PGF2α in humans and rats; present in normal human urine at concentrations of 200-300 pg/ml.
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17-phenyl trinor Prostaglandin F2a ethyl amide-d4
Cayman ChemicalAn internal standard for the quantification of 17-phenyl trinor PGF2α ethyl amide by GC- or LC-MS.
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11-dehydro Thromboxane B2-d4
Cayman Chemical11-dehydro TXB2-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 11-dehydro TXB2 by GC- or LC-mass spectrometry. 11-dehydro TXB2 is a urinary metabolite of TXB2 and TXA2.
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11-dehydro Thromboxane B3
Cayman Chemical11-dehydro TXB3 is a urinary metabolite of TXA3 in humans with enhanced dietary intake of EPA.