Bifonazole is an imidazole antifungal that also exhibits anticancer activity. Bifonazole inhibits calmodulin, HMG-CoA reductase, and 14-a demethylase in fungi such as dermatophytes. Bifonazole also decreases cell viability and induces Ca2+-dependent apoptosis in prostate cancer cells and melanoma cells.

Synonym(s): Mycosporan, 1-(^a,4-Diphenylbenzyl)imidazole Formula: C22H18N2 Formula weight: 310.39 Purity: 99% CAS Number: 60628-96-8 Harmonized Tariff Code:  2933.29 Hazard Statements: H302 Harmful if swallowed. Precautionary Statements: P264-P270-P301+P312-P330-P501a Wash…

CAS: 60628-96-8 EC No: 262-336-6 MDL No: MFCD00865567 RTECS: NI3517000 Powder Molecular Formula: C₂₂H₁₈N₂ MW: 310.39

A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria; a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM, IC₅₀ = 270 nM).

CAS No.: 60628-96-8