Antineoplastic antibiotic produced by growth of Streptomyces chrysomallys and other species of Streptomyces .

CAS No.: 50-76-0 UN No.: UN2811 Class: 6.1 Pkg. Group: PG II

Synonym(s): Dactinomycin, Actinomycin C1 Formula: C62H86N12O16 Formula weight: 1255.40 CAS Number: 50-76-0 UN Number: UN3462 Hazard Class: 6.1 Packing Group: II Harmonized Tariff Code:  2941.90 Hazard Statements: H300-H360-H351 Fatal if swallowed. May damage fertility or…

A cyclic polypeptide-containing anticancer antibiotic that binds to DNA and blocks transcription by interfering with RNA synthesis; ~10 nM promotes cell death in a variety of tumors.

Actinomycin D is a polypeptide antibiotic produced from Streptomyces; it exhibits anticancer chemotherapeutic activity but does not display antibacterial benefit. Actinomycin D is clinically used to treat various cancers and is one component of the VAC chemotherapy regimen. Actinomycin D binds DNA,…

Antineoplastic antibiotic produced by growth of Streptomyces chrysomallys and other species of Streptomyces. A potent antibiotic that binds to the GpC steps of DNA For in vitro lab use only. Not for human use or consumption. Appearance: Solid Boiling Point: 1386.05 °C at 760…

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and…

Actinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…

A class of polypeptide antibiotics isolated from the Steptomyces soil bacteria. Actinomycin D inhibits transcription by binding to DNA at the transcription initiation complex and therefore preventing elongation by the RNA polymerase. Supplied as 50μl 10mM solution. Features …