Each donor unit used in the preparation of the product was tested and found negative for Anti-HIV 1/2, HBsAg, Anti-HCV and HIV-1 Ag by FDA approved methods or CE approved methods. Used as an immunological challenge in studies of mechanisms of immunotolerance.

From Bovine Plasma Prepared as Cohn Fraction II γ-Globulin can be used as a co-precipitant in RIA methods employing polyethylene glycol or ammonium sulfate precipitate. Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.