The V5 tag is a polypeptide of GKPIPNPLLGLDST amino acid sequence that can be added to a target protein using recombinant DNA technology. It can be fused to the N-terminus, C-terminus or inserted in an internal region of the protein to facilitate detection and purification. An anti-V5 tag antibody…

Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the ß trefoil structure. In vivo, FGF-basic is produced by a variety of cells, including…

Actions of neuropeptide galanin are mediated by three G-protein coupled receptors, GalR1, GalR2, and GalR3. Human GALR2 was shown to couple to phospholipase C and to be involved in the elevation of intracellular calcium levels. GALR2 mRNA shows a wide distribution in the brain (mammillary nuclei,…

CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of…

Transforming growth factor beta-2 (TGF-ß2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains…

dCTP (100 mM) ≥99% HPLC

Ghrelin is the first natural appetite stimulant found to be made outside the brain. It is one of a complex array of natural substances that carry messages between the brain and the digestive system. Secreted by specialized cells in the stomach and the upper part of the small intestine, ghrelin acts…

This peptide (β-Amyloid (1-42), human, 0.5mg) is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of…

Sharing 79% sequence identity with human Tumor Necrosis Factor-alpha (hTNF-a), mouse Tumor Necrosis Factor-alpha (mTNF-a) is a cytokine mainly expressed by immune cells [1] . A type II transmembrane protein, TNF-a is further proteolytically processed to a soluble form [2] . The trimeric active…

Tocilizumab also known as atlizumab, is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration. It has a high affinity to IL-6R and blocks the IL-6 signaling by preventing the formation of the IL-6/IL-6R complex. Tocilizumab is used for the trea™ent of…

GenScript THE ™ DYKDDDDK Tag Antibody [HRP], mAb, Mouse is HRP conjugated THE™ Anti-DYKDDDDK Monoclonal Antibody (Mouse) (A00187) purified from mice ascites by protein A affinity column. The antibody is suitable for detecting the expression level of DYKDDDDK in fusion proteins.

Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80% sequence homology with the Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells and dendritic…

eBlot L1 is a highly efficient wet protein transfer system, which uses a patented technology developed by GenScript. eBlot L1 combines the high stability and efficiency of the traditional wet transfer with the rapidness and convenience of the semi-dry transfer system. The device allows the…

5-Hydroxytryptamine (5-HT, also commonly known as serotonin) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals. In the periphery, 5-HT mediates gastrointestinal motility, platelet aggregation, and contraction of blood vessels. Many functions of the…

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is a 40-60 kDa variably glycosylated atypical member of the immunoglobulin superfamily and…

Fibroblast Growth Factor-basic (FGF-basic) , also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the ß trefoil structure. In vivo , FGF-basic is produced by a variety of cells, including…

Interleukin-4 (IL-4), also known as BSF-1 and Lymphocyte stimulatory factor 1, is a secreted cytokine belonging to the IL-4/IL-13 family. It is produced by mast cells, T cells and bone marrow stromal cells. IL-4 signals through two receptor complexes: theIL4Ra/common ? chain and the IL4Ra-IL-13…

Human secretin stimulates the secretion of bicarbonate by the pancreas and inhibits the production of gastrin and acid production in the stomach. Human secretin also potentiates the release of digestive enzymes from the pancreas triggered by cholecystokinin.

Multiple Tag is a specially designed fusion protein that can serve as an excellent positive control for western and dot blots. The fusion protein has an apparent molecular weight of ~40 kDa on SDS-PAGE and it contains 16 commonly used tags from N terminus to C terminus in the order as shown in the…

Interleukin-8 is one of the first discovered chemokines and belongs to the CXCL family, in which the first two conserved cysteines are separated by one residue. In vivo , IL-8 exists in two forms: a 77 a.a. protein produced by endothelial cells, and the more active 72 a.a. protein produced by…

Protein A affinity chromatography resin is the most commonly applied method for the isolation and purification of IgG. Protein A is a cell wall component found in several strains of Staphylococcus aureus . It has five high affinity binding sites capable of binding specifically to the Fc region of…

Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca 2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability,…

MES SDS Running Buffer is formulated for running ExpressPlus™ and SurePAGE™, Bis-Tris gels. This buffer is ideal for separating small- and medium- sized proteins. For separation of large- to medium- sized proteins, Tris-MOPS SDS buffer (M00138) is recommended. Reconstitute with 1000…

Taq DNA Polymerase is a thermostable DNA Polymerase isolated from an E. coli strain that carries the Taq DNA polymerase gene. Taq DNA Polymerase is the most common polymerase used for PCR. Note: This product is supplied with 10X reaction buffer containing 15 mM magnesium chloride. dNTP…

This is fibronectin derived, integrin-binding peptide. It may be used for PEG hydrogel preparation.

Proteinase-activated receptors (PAR) are a subfamily of G-protein coupled, seven-transmembrane domain receptors, which are cleaved within the aminoterminal exodomain by certain serine proteinases at a specific peptide bond. Trypsin and mast cell tryptase, and more recently, the activated…

The short form of D2 (D2S) and the long form (D2L) are two isoforms that contribute differentially to dopamine signaling in both prefrontal cortex and striatum. The D2 dopamine receptor, short form (D2s) has been shown to stimulate phospholipase D (PLD) activity independent of the activation of…

Broad Multi Color Pre-Stained Protein Standard is a special-designed protein standard. The standard is a mixture of ten highly purified prestained proteins ranging from 5 kDa to 270 kDa, covalently coupled with four different chromophores. The 30 kDa band is red, 50 kDa band is green, 270 kDa band…

GenScript Protein G MagBeads MX are superparamagnetic beads of average 40 µm in diameter, covalently coated with recombinant Protein G. The beads are supplied as 25% slurry in 20% ethanol. The Protein G MagBeads MX have a binding capacity of more than 25 mg Human IgG per 1 ml settled beads. …

Adalimumab (Humira) is a humanized monoclonal antibody that’s approved by the U.S. Food and Drug Administration for the trea™ent of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, chronic psoriasis, hidradenitis…

Daratumumab (Darzalex) is a human IgG1k monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of multiple myeloma. It binds with high affinity to CD38, which is highly expressed on the surface of multiple myeloma cells. Daratumumab can make immune system to…

The Product contain 1000 U Taq DNA Polymerase (Cat. No. E00007) and 0.5 ml of 10 mM dNTP (Cat. No. D0056). The Taq DNA Polymerase is supplied with 10X reaction buffer (Cat. No. B0005) containing 15 mM magnesium chloride.