The choice of columns for analysis of difficult compounds by HPLC YMC-Pack Pro C18 columns start with a tightly controlled, highly purified silica gel, followed by a high-coverage C18 bonding and finish with a unique endcapping procedure utilizing Lewis acid-Lewis base chemistry. 2 µm particle size…

ODS-A in 120Å pore size is the first choice of many chromatographers for high performance reversed phase separations. It has selectivity for the separation of a wide range of organic compounds found in pharmaceutical, chemical and biotechnology industries. ODS-A is a high coverage, fully endcapped…

YMC-Pack C4 (Butyl) columns are less hydrophobic than C8 or C18 packings, and generally utilize more aqueous eluents than either of these reversed phase column types. When compared to C8 and C18 columns using the same eluent, C4 columns show significantly Application: For…

YMC-Pack C4 (Butyl) columns are less hydrophobic than C8 or C18 packings, and generally utilize more aqueous eluents than either of these reversed phase column types. When compared to C8 and C18 columns using the same eluent, C4 columns show significantly shorter retention for non-polar compounds.…

The high purity silica found in YMC-Pack Silica columns provides virtually complete sample recovery. The absence of silica impurities reduces non-specific sample adsorption which lowers sample recovery and may cause unusual peak shapes. The totally porous nature of the silica found in YMC-Pack…

SUMICHIRAL OA columns are high-performance chiral columns for enantiomer separation by HPLC. On SUMICHIRAL OA columns direct separation of various enantiomers can be realized effectively. Enantiomeric separation is achieved from the various diastereomeric interactions such as hydrogen bonding,…

YMC-Pack ODS-A has a highly endcapped surface structure and appropriate hydrophobicity for separation of a wide range of compounds. It is produced under strict quality control with respect to 50 or more parameters in order to ensure stable quality. This product is highly regarded as the standard…

C8 is the most commonly used column type following C18. YMC Octyl columns are prepared from exhaustive bonding of a monomeric octylsilane to totally spherical and porous silica gels. The functionalized silica is then treated with a endcapping process. This produces a moderate 10% carbon loading on…

YMC-Pack C4 (Butyl) columns are less hydrophobic than C8 or C18 packings, and generally utilize more aqueous eluents than either of these reversed phase column types. When compared to C8 and C18 columns using the same eluent, C4 columns show significantly shorter retention for non-polar compounds.…

ODS-AM is a high carbon load C18 packing that is similar in selectivity to ODS-A. The major difference between these bonded phases is that ODS-AM has extremely tight specification criteria which provides excellent peak shape and more reproducible separation. Application: For Alkaloids Long-term…

The high purity silica found in YMC-Pack Silica columns provides virtually complete sample recovery. The absence of silica impurities reduces non-specific sample adsorption which lowers sample recovery and may cause unusual peak shapes. The totally porous nature of the silica found in YMC-Pack…

ODS-A in 120Å pore size is the first choice of many chromatographers for high performance reversed phase separations. It has selectivity for the separation of a wide range of organic compounds found in pharmaceutical, chemical and biotechnology industries. ODS-A is a high coverage, fully endcapped…

Handy connector 2 resists pressure to ca. 42 MPa. Handy connector 2 is suitable for connection to the injection side of a column, to which high pressure is applied. It is also useful for connection of a guard column or a precolumn filter. Be aware that Handy connector 2 cannot be connected to"…

YMC-Pack TMS columns are bonded with trimethylmonochlorosilane to create a phase with intermediate polarity for analysis of extremely hydrophobic compounds using conventional reversed-phase solvents and highly polar compounds using highly aqueous solvents. The unique chemistry of TMS is also…

In a reversed-phase mode, Cyano columns are the most polar and least retentive of all reversed-phase packings. Extremely hydrophobic compounds, which do not elute on standard C18 and C8 packings with typical reversed-phase eluents, can be chromatographed using Cyano columns. In addition, the unique…

YMC-Pack TMS columns are bonded with trimethylmonochlorosilane to create a phase with intermediate polarity for analysis of extremely hydrophobic compounds using conventional reversed-phase solvents and highly polar compounds using highly aqueous solvents. The unique chemistry of TMS is also…

Phenyl columns provide unique selectivity when compared to aliphatic straight chain reversed phases such as ODS, C8 and C4. The p electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to non-aromatic species. Phenyl also has application as an…

YMC-Pack C4 (Butyl) columns are less hydrophobic than C8 or C18 packings, and generally utilize more aqueous eluents than either of these reversed phase column types. When compared to C8 and C18 columns using the same eluent, C4 columns show significantly shorter retention for non-polar compounds.…

YMC-Triart C18 is a hybrid silica-based ODS column emphasizing durability, low operating pressure, and excellent performance. YMC-Triart C18 has been developed and is manufactured using state-of-the-art technologies that define materials, granulation, and surface modification. Application: For…

YMC-Pack Diol-NP shows retention behavior of normal-phase chromatography when it is used with low-polarity mobile phases. Hydroxyl groups on the surface of the stationary phase act as polar groups. YMC-Pack Diol-NP is as widely applicable to normal-phase separation as silica gel. It is also useful…

In a reversed-phase mode, Cyano columns are the most polar and least retentive of all reversed-phase packings. Extremely hydrophobic compounds, which do not elute on standard C18 and C8 packings with typical reversed-phase eluents, can be chromatographed using Cyano columns. In addition, the unique…

YMCbasic is a unique reversed-phase column designed for analysis of pharmaceuticals and other basic compounds. YMCbasic utilizes a novel silica synthesis and state-of-art silane bonding to create a column which gives true reversed-phase character, high resolution and excellent peak shape for the…

ODS-AQ is a unique reversed-phase material with both a hydrophobic high carbon loading and a relatively hydrophilic surface. Because of the hydrophilic surface, ODS-AQ can be "wetted" with polar eluents. ODS-AQ provides chromatographers reproducible retention and excellent peak shape in highly…

YMC-Pack NH2 is a normal-phase separation column utilizing the polarity of primary amino groups. It is also applicable to separations utilizing weak anion exchange. YMC-Pack NH2 is often used for separation of sugars. Application: For Nucleotides Silica gel chemically bonded with aminopropyl…

Hydrosphere C18 is designed to maintain adequate hydrophilicity on the packing surface for superior separation of hydrophilic compounds. Hydrophilic compounds are retained with much greater affinity than with conventional ODS columns, permitting the product to be used with 100% water eluent, a…

YMC-Pack Diol is a size exclusion chromatography column utilizing a silica gel base. Diol-120, 200, and 300 are suitable for separation or molecular weight determination of proteins with molecular weights of 10,000 to 1,000,000. Diol-60 is the most suitable for separation of peptides of…

Phenyl columns provide unique selectivity when compared to aliphatic straight chain reversed phases such as ODS, C8 and C4. The p electrons of the phenyl group can interact with the aromatic ring of an analyte to increase retention relative to non-aromatic species. Phenyl also has application as an…

All phases in the Pro-family are ideal for the analysis of all types of organic molecules but specifically basic and metal chelating compounds. The ultrapure silica and very low residual silanol activity means that these columns frequently do not require the use of ion-pairing reagents or…

C8 is the most commonly used column type following C18. YMC Octyl columns are prepared from exhaustive bonding of a monomeric octylsilane to totally spherical and porous silica gels. The functionalized silica is then treated with a endcapping process. Application: For Anti-Human Immunodeficiency…

YMC Carotenoid is a silica-based reversed-phase column chemically bonded with a triacontyl (C30) group, and is useful for separating geometric isomers of carotenoids. It is useful as a column with different separation selectivity when it is difficult to separate compounds other than carotenoids…

SUMICHIRAL OA columns are high-performance chiral columns for enantiomer separation by HPLC. On SUMICHIRAL OA columns direct separation of various enantiomers can be realized effectively. Enantiomeric separation is achieved from the various diastereomeric interactions such as hydrogen bonding,…

C8 is the most commonly used column type following C18. YMC Octyl columns are prepared from exhaustive bonding of a monomeric octylsilane to totally spherical and porous silica gels. The functionalized silica is then treated with a endcapping process. Application: For Anti-Human Immunodeficiency…