Biologically Active Small Molecules, UN1888, 500 µg
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Palmitoleoyl 3-carbacyclic Phosphatidic Acid
Cayman ChemicalA cyclic LPA analog that contains the 16:1 fatty acid, palmitoleate, at the sn-1 position; at 25 μM inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers without affecting proliferation; significantly inhibits autotaxin (IC50 = 620 nM).
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Oleoyl 3-carbacyclic Phosphatidic Acid
Cayman ChemicalA cyclic LPA analog that contains the 18:1 fatty acid, oleate, at the sn-1 position; at 25 μM, inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers without affecting proliferation; at 0.1-1.0 μM, significantly inhibits autotaxin and antagonizes LPA1 (IC50 = 836…
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