Biologically Active Small Molecules, UN1230, Cayman Chemical, 877617-46-4
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F-Amidine (trifluoroacetate salt)
Cayman ChemicalInhibits PAD4 activity (IC50 = 21.6 μM) as well as PAD1 and PAD3 activity (IC50s = 29.5 and 350 μM, respectively); cytotoxic to HL-60, MCF-7, and HT-29 cancer cell lines (IC50s = 0.5, 0.5 and 1 μM, respectively).
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