Biologically Active Small Molecules, UN1170, 141022-99-3

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141022-99-3 UN1170 Biologically Active Small Molecules

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  • PTK is an analog of palmitic acid in which the COOH group is replaced by trifluoromethyl ketone. In P388D1 cells, PTK inhibits iPLA2 activity with an IC50 value of 3.8 µM. A related compound, ATK is a less potent inhibitor of iPLA2 with an IC50 value of 15 µM. PTK…