Biologically Active Small Molecules, Cayman Chemical, UN2811, 50 mg, 86639-52-3
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SN 38
Cayman ChemicalThe active metabolite of irinotecan that potently inhibits DNA topoisomerase I; more cytotoxic to HT-29 colon cancer cells (IC50 = 8.8 nM) compared to irinotecan (IC50 > 100 nM).
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