Biologically Active Small Molecules, Cayman Chemical, UN2811, 104987-11-3
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FK-506
Cayman ChemicalA potent, clinically-useful immunosuppressant; binds to FK-506 binding protein 12 (Ki = 0.2 nM) to inhibit calcineurin; regulates NO neurotoxicity, neurotransmitter release, and regulation of Ca2+ release via the ryanodine and IP3 receptors.
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