An internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-MS.

5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (±)5-HETE lactone to inhibit RBL-1 cell 5-LO (IC₅₀ = 27 µM) may be entirely due to the 5(S) isomer, but the enantiomers…

An internal standard for the quantification of PGF2α-1-glyceryl ester by GC- or LC-MS.

5(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 5(S)-HETE by GC- or LC-mass spectrometry (MS).

A novel CYP450 metabolite of 2-AG in the kidney; acts as a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells at concentrations as low as 100 nM and doubling cell proliferation rates at 1 µM.

An internal standard for the quantification of 13-OxoODE by GC- or LC-MS.

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS).

An internal standard for the quantification of ent-8-iso-15(S)-PGF2α by GC- or LC-MS.

An internal standard for the quantification of 9-OxoODE by GC- or LC-MS.

A non-enzymatic, free radical peroxidation product of arachidonic acid; acts as a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively; approximately ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation…

An internal standard for the quantification of 2-AG by GC- or LC-MS.

12-epi Leukotriene B4-d4 (12-epi LTB4-d4) contains four deuterium atoms at the 6, 7, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 12-epi LTB4 by GC- or LC-mass spectrometry.

13(S)-HODE-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of 13(S)-HODE by GC- or LC-MS.

An internal standard for the quantification of 5-oxoETE by GC- or LC-MS.

A non-enzymatic, free radical peroxidation product of arachidonic acid; acts as a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 31 and 54 nM, respectively.

An internal standard for the quantification of ent-8-iso-PGF2α by GC- or LC-MS.

20-HETE-d6 contains six deuterium atoms at the 16, 16', 17, 17', 18 and 18' positions. It is intended for use as an internal standard for the quantification of 20-HETE by GC- or LC-mass spectrometry.

An internal standard for the quantification of LTB4 by GC- or LC-MS.

15(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC- or LC-MS.

An initial metabolite of LTB4 with significantly reduced biological activity.

The most abundant isoprostane product formed during lipid peroxidation; detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and CSF of patients with Alzheimer’s disease.

(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone is an inhibitor of 5-LO from rat basophilic leukemia cells with an IC₅₀ of 27 µM. The lactone is several…