Biologically Active Small Molecules, Cayman Chemical, UN1231, 50 µg
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Prostaglandin F2a-d4
Cayman ChemicalAn internal standard for the quantification of PGF2α by GC- or LC-MS.
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tetranor-PGAM
Cayman ChemicalA dehydration product of tetranor-PGEM that can be measured as a surrogate for tetranor-PGEM levels in urine.
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17-trans Prostaglandin E3
Cayman Chemical17-trans PGE3 is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids. There are no published reports on the biological activity of this compound.
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Clasto-Lactacystin ß-lactone
Cayman ChemicalActive metabolite of lactacystin, a widely used selective inhibitor of the 20S proteasome, with at least 10 times better activity; irreversibly alkylates subunit X of the 20S proteasome.
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Prostaglandin A2-d4
Cayman ChemicalAn internal standard for the quantification of PGA2 by GC- or LC-MS.
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13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
Cayman ChemicalAn internal standard for quantification of 13,14-dihydro-15 (R,S)-hydroxy-16,16-difluoro-Prostaglandin E1, a metabolite of a bicyclic PGE1 derivative used in the treatment of chronic constipation, by GC- or LC-mass spectrometry (MS).
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Tafluprost-d4
Cayman ChemicalContains four deuterium atoms at the 3', 3', 4', and 4' positions; is intended for use as an internal standard for the quantification of tafluprost by GC-or LC-mass spectrometry.
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11ß-13,14-dihydro-15-keto Prostaglandin F2a
Cayman ChemicalA metabolite of PGD2 via the 15-hydroxy PGDH pathway.
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13,14-dihydro-15-keto-tetranor Prostaglandin F1ß
Cayman ChemicalA major urinary metabolite of PGE2 that is excreted in guinea pig urine at a concentration range of 1.34-2.74.
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4-hydroxy Hexenal-d3
Cayman ChemicalAn internal standard for the quantification of 4-hydroxy hexenal by GC- or LC-MS.
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8-iso Prostaglandin F1a-d9
Cayman Chemical8-iso PGF1α-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of 8-iso PGF1α by GC- or LC-MS.
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Fluprostenol-d4
Cayman ChemicalFluprostenol-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of fluprostenol by GC- or LC-MS.
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13,14-dihydro-15-keto Prostaglandin E1-d4
Cayman Chemical13,14-dh-15-k PGE1-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dh-15-k PGE1 by GC- or LC-mass spectrometry.
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Prostaglandin B2-d4
Cayman ChemicalAn internal standard for the quantification of PGB2 by GC- or LC-MS.
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Tafluprost (free acid)-d4
Cayman ChemicalContains four deuterium atoms at the 3', 3', 4', and 4' positions; is intended for use as an internal standard for the quantification of tafluprost (free acid) by GC-or LC-mass spectrometry.
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tetranor-PGJM
Cayman ChemicalAn expected J-ring, urinary PGD2 metabolite that may serve as a useful control in the analysis of PGD2 biosynthesis.
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11-dehydro Thromboxane B2
Cayman ChemicalThromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis. The mean plasma…
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Prostaglandin B3
Cayman ChemicalPGB3 is a non-enzymatic dehydration product resulting from the treatment of PGE3 with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ, PGB3 exhibited a Ki value greater than 1 mM.{11138} In contrast, PGB1 and PGB2 showed…
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8-iso Prostaglandin F2a-d4
Cayman ChemicalAn internal standard for the quantification of 8-iso PGF2α by GC- or LC-MS.
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(±)12(13)-EpOME
Cayman Chemical(±)12(13)-EpOME is the 12,13-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. The toxicity and biosynthesis of (±)12(13)-EpOME have not been well differentiated from (±)9(10)-EpOME, but have been presumed to be essentially the same.
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Prostaglandin D1-d4
Cayman ChemicalAn internal standard for the quantification of PGD1 by GC- or LC-MS.
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(±)12(13)-EpOME-d4
Cayman Chemical(±)12(13)-EpOME-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of latanoprost by GC- or LC-MS.
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tetranor-PGDM lactone
Cayman ChemicalA closed form of tetranor-PGDM whose formation in biological samples has not been evaluated.
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Prostaglandin D2-d9
Cayman ChemicalAn internal standard for the quantification of PGD2 by GC- or LC-MS.
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13,14-dihydro-15-keto Prostaglandin E2-d4
Cayman ChemicalAn internal standard for the quantification of 13,14-dihydro-15-keto PGE2 by GC- or LC-MS.
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Prostaglandin E3
Cayman ChemicalPGE3 is formed via the COX metabolism of EPA. In human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases IOP from 21 mmHg to about 17 mmHg.
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(±)12(13)-DiHOME-d4
Cayman Chemical(±)12(13)-DiHOME-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of (±)12(13)-DiHOME by GC- or LC-mass spectrometry (MS).
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17-phenyl trinor Prostaglandin F2a-d4
Cayman ChemicalAn internal standard for the quantification of 17-phenyl trinor PGF2α by GC- or LC-MS.
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(±)9(10)-EpOME-d4
Cayman ChemicalAn internal standard for the quantification of latanoprost by GC- or LC-mass spectrometry (MS).
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13,14-dihydro-15-keto Prostaglandin D2-d4
Cayman Chemical13,14-dihydro-15-keto Prostaglandin D2-d4 (13,14-dihydro-15-keto PGD2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2 by GC- or LC-mass spectrometry.