Biologically Active Small Molecules, Cayman Chemical, 334998-36-6, Chemicals

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Chemicals 334998-36-6 Cayman Chemical Biologically Active Small Molecules

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  • Cayman Chemical

    A potent inhibitor of hedgehog-induced cellular activity (IC50 = 100-200 nM); binds directly with the pathway activator Smo (Ki = 44 nM); blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of basaloid lesions triggered by ultraviolet light in…