Biologically Active Small Molecules, Chemicals, 14028-44-5
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Amoxapine
LKT LabsAmoxapine is a tricyclic antidepressant that acts as an antagonist at 5-HT2/3/6/7 receptors, D2/3/4 receptors, H1 histamine receptors, a1-adrenergic receptors, and also on the serotonin transporter (SERT) and norepinephrine transporter (NET). Amoxapine also acts as an antagonist at hERG K+…
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Amoxapine
Cayman ChemicalA tetracyclic antidepressant that inhibits norepinephrine and serotonin reuptake, binding the respective transporters with Kd values of 16 and 58 nM; acts as either an antagonist or inverse agonist at 5-HT2A, 2B, 2C, 3, 6, 7 (Kis = 1 and 2 nM for 5-HT2A and 5-HT2C), D2, 3, 4 (Kd = 160 nM for D2),…
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