Biologically Active Small Molecules, 606-58-6
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Toyocamycin
Cayman ChemicalA natural adenosine analog that prevents IRE1α-induced mRNA cleavage (IC50 = 80 nM) and inhibits constitutive activation of XBP1 in multiple myeloma cell lines; used to study IRE1α action in the endoplasmic reticulum stress response.
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